Wednesday, September 28, 2016

Actulose




Actulose may be available in the countries listed below.


Ingredient matches for Actulose



Lactulose

Lactulose is reported as an ingredient of Actulose in the following countries:


  • Bangladesh

International Drug Name Search

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Tuesday, September 27, 2016

Proviron




Proviron may be available in the countries listed below.


Ingredient matches for Proviron



Mesterolone

Mesterolone is reported as an ingredient of Proviron in the following countries:


  • Algeria

  • Australia

  • Austria

  • Belgium

  • Benin

  • Brazil

  • Burkina Faso

  • Cameroon

  • Central African Republic

  • Chad

  • Chile

  • Colombia

  • Congo

  • Cote D'ivoire

  • Czech Republic

  • Dominican Republic

  • Ethiopia

  • Gabon

  • Georgia

  • Greece

  • Hungary

  • Indonesia

  • Israel

  • Italy

  • Luxembourg

  • Madagascar

  • Mali

  • Mauritania

  • Mauritius

  • Mexico

  • Niger

  • Oman

  • Peru

  • Philippines

  • Poland

  • Portugal

  • Senegal

  • Serbia

  • South Africa

  • Spain

  • Sri Lanka

  • Togo

  • Turkey

International Drug Name Search

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Amfetamine Sulphate




Amfetamine Sulphate may be available in the countries listed below.


Ingredient matches for Amfetamine Sulphate



Amfetamine

Amfetamine Sulphate (BANM) is also known as Amfetamine (Rec.INN)

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.
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Galinocort




Galinocort may be available in the countries listed below.


Ingredient matches for Galinocort



Betamethasone

Betamethasone 17α-valerate (a derivative of Betamethasone) is reported as an ingredient of Galinocort in the following countries:


  • Greece

International Drug Name Search

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Acuatim




Acuatim may be available in the countries listed below.


Ingredient matches for Acuatim



Nadifloxacin

Nadifloxacin is reported as an ingredient of Acuatim in the following countries:


  • Indonesia

  • Japan

International Drug Name Search

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Advil Childrens


Generic Name: ibuprofen (EYE bue PROE fen)

Brand Names: Advil, Advil Childrens, Advil Junior Strength, Advil Liquigel, Advil Migraine, Advil Pediatric, Children's Ibuprofen Berry, Genpril, IBU, Midol IB, Midol Maximum Strength Cramp Formula, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Nuprin


What is Advil Childrens (ibuprofen)?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.


Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury.


Ibuprofen may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Advil Childrens (ibuprofen)?


This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use ibuprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.


This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen, especially in older adults.

Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.


Do not take more of this medication than is recommended. An overdose of ibuprofen can cause damage to your stomach or intestines. Use only the smallest amount of ibuprofen needed to get relief from your pain, swelling, or fever.

What should I discuss with my healthcare provider before taking Advil Childrens (ibuprofen)?


Do not use ibuprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG).


This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen, especially in older adults.


You should not use this medication if you are allergic to ibuprofen, aspirin or other NSAIDs.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:



  • a history of heart attack, stroke, or blood clot;




  • heart disease, congestive heart failure, high blood pressure;




  • a history of stomach ulcers or bleeding;




  • asthma;




  • polyps in your nose;



  • liver or kidney disease;


  • systemic lupus erythematosus (SLE);




  • a bleeding or blood clotting disorder; or




  • if you smoke.




FDA pregnancy category D. Taking ibuprofen during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using ibuprofen. It is not known whether ibuprofen passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child without the advice of a doctor.

How should I take Advil Childrens (ibuprofen)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Do not take more of this medication than is recommended. An overdose of ibuprofen can cause damage to your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). Use only the smallest amount of ibuprofen needed to get relief from your pain, swelling, or fever. Take ibuprofen with food or milk to lessen stomach upset. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The ibuprofen chewable tablet must be chewed before you swallow it.


If you take ibuprofen for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.


Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

What happens if I miss a dose?


Since ibuprofen is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.

What should I avoid while taking Advil Childrens (ibuprofen)?


Avoid taking ibuprofen if you are taking aspirin to prevent stroke or heart attack. Ibuprofen can make aspirin less effective in protecting your heart and blood vessels. If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the aspirin (non-enteric coated form). Ask a doctor or pharmacist before using any other cold, allergy, or pain medicine. Ibuprofen and other NSAIDs are contained in many combination medicines. Taking certain products together can cause you to get too much ibuprofen. Check the label to see if a medicine contains ibuprofen or similar NSAIDs (aspirin, naproxen, ketoprofen). Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Advil Childrens (ibuprofen) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking ibuprofen and seek medical attention or call your doctor at once if you have any of these serious side effects:

  • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;




  • black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;




  • swelling or rapid weight gain;




  • urinating less than usual or not at all;




  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);




  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;




  • bruising, severe tingling, numbness, pain, muscle weakness; or




  • severe headache, neck stiffness, chills, increased sensitivity to light, and/or seizure (convulsions).



Less serious side effects may include:



  • upset stomach, mild heartburn, diarrhea, constipation;




  • bloating, gas;




  • dizziness, headache, nervousness;




  • skin itching or rash;




  • blurred vision; or




  • ringing in your ears.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Advil Childrens (ibuprofen)?


Ask your doctor before using an antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all other medicines you use, especially:



  • aspirin or other NSAIDs such as naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;




  • heart or blood pressure medicine such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;




  • lithium (Eskalith, Lithobid);




  • diuretics (water pills) such as furosemide (Lasix);




  • methotrexate (Rheumatrex, Trexall);




  • steroids (prednisone and others); or




  • a blood thinner such as warfarin (Coumadin, Jantoven).



This list is not complete and other drugs may interact with ibuprofen. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Advil Childrens resources


  • Advil Childrens Side Effects (in more detail)
  • Advil Childrens Use in Pregnancy & Breastfeeding
  • Drug Images
  • Advil Childrens Drug Interactions
  • Advil Childrens Support Group
  • 0 Reviews for Advil Childrens - Add your own review/rating


  • Advil Childrens Prescribing Information (FDA)

  • Ibuprofen Prescribing Information (FDA)

  • Ibuprofen Professional Patient Advice (Wolters Kluwer)

  • Ibuprofen Monograph (AHFS DI)

  • Advil Consumer Overview

  • Advil Prescribing Information (FDA)

  • Advil Advanced Consumer (Micromedex) - Includes Dosage Information

  • Advil MedFacts Consumer Leaflet (Wolters Kluwer)

  • Advil Migraine Prescribing Information (FDA)

  • Caldolor Prescribing Information (FDA)

  • Caldolor Advanced Consumer (Micromedex) - Includes Dosage Information

  • Caldolor Injection MedFacts Consumer Leaflet (Wolters Kluwer)

  • Caldolor Consumer Overview

  • IBU MedFacts Consumer Leaflet (Wolters Kluwer)

  • Ibutilide Fumarate Monograph (AHFS DI)

  • Motrin Prescribing Information (FDA)

  • Motrin Consumer Overview

  • Motrin IB Prescribing Information (FDA)

  • Motrin Junior Strength Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • NeoProfen Prescribing Information (FDA)



Compare Advil Childrens with other medications


  • Fever
  • Headache
  • Muscle Pain
  • Pain
  • Period Pain
  • Spondylolisthesis


Where can I get more information?


  • Your pharmacist can provide more information about ibuprofen.

See also: Advil Childrens side effects (in more detail)


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Pimecrolimus




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

D11AH02

CAS registry number (Chemical Abstracts Service)

0137071-32-0

Chemical Formula

C43-H68-Cl-N-O11

Molecular Weight

810

Therapeutic Categories

Dermatological agent

Immunosuppressant

Antipruritic

Chemical Name

(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-12-[(E)-2-[(1R,3R,4S)-4-Chloro-methoxycyclohexyl]-1-methylvinyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrid (WHO)

Foreign Names

  • Pimecrolimusum (Latin)
  • Pimecrolimus (German)
  • Pimecrolimus (French)
  • Pimecrolimus (Spanish)

Generic Names

  • Pimecrolimus (OS: USAN, BAN)
  • 33-Epi-chloro-33-desoxyascomycin (IS)
  • ASM 981 (IS)
  • Elidel (IS)
  • SDZ ASM 981 (IS)

Brand Names

  • Elidel
    Euro, Netherlands; Novartis, Argentina; Novartis, Austria; Novartis, Australia; Novartis, Bosnia & Herzegowina; Novartis, Bangladesh; Novartis, Belgium; Novartis, Bahrain; Novartis, Brazil; Novartis, Canada; Novartis, Switzerland; Novartis, Chile; Novartis, Colombia; Novartis, Czech Republic; Novartis, Germany; Novartis, Denmark; Novartis, Ecuador; Novartis, Estonia; Novartis, Spain; Novartis, Finland; Novartis, United Kingdom; Novartis, Georgia; Novartis, Greece; Novartis, Hong Kong; Novartis, Croatia (Hrvatska); Novartis, Hungary; Novartis, Indonesia; Novartis, Israel; Novartis, Iceland; Novartis, Italy; Novartis, Lithuania; Novartis, Luxembourg; Novartis, Latvia; Novartis, Malta; Novartis, Mexico; Novartis, Malaysia; Novartis, Netherlands; Novartis, Norway; Novartis, New Zealand; Novartis, Oman; Novartis, Panama; Novartis, Philippines; Novartis, Poland; Novartis, Portugal; Novartis, Romania; Novartis, Serbia; Novartis, Russian Federation; Novartis, Sweden; Novartis, Singapore; Novartis, Slovenia; Novartis, Slovakia; Novartis, Thailand; Novartis, Turkey; Novartis, Taiwan; Novartis, United States; Novartis, Venezuela; Novartis, South Africa


  • Rizan
    Laboratorios Dr Esteve, Spain

International Drug Name Search

Glossary

BANBritish Approved Name
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.
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Amiodarona




Amiodarona may be available in the countries listed below.


Ingredient matches for Amiodarona



Amiodarone

Amiodarone is reported as an ingredient of Amiodarona in the following countries:


  • Peru

Amiodarone hydrochloride (a derivative of Amiodarone) is reported as an ingredient of Amiodarona in the following countries:


  • Chile

  • Colombia

  • Romania

International Drug Name Search

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xylometazoline Nasal


zye-loe-me-TAZ-oh-leen


Commonly used brand name(s)

In the U.S.


  • Otrivin

  • Otrivin Pediatric

Available Dosage Forms:


  • Spray

  • Solution

Therapeutic Class: Decongestant


Chemical Class: Imidazoline


Uses For xylometazoline


Xylometazoline is used for the temporary relief of congestion or stuffiness in the nose caused by hay fever or other allergies, colds, or sinus trouble.


xylometazoline may also be used for other conditions as determined by your doctor.


xylometazoline is available without a prescription.


Before Using xylometazoline


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For xylometazoline, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to xylometazoline or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Children may be especially sensitive to the effects of xylometazoline. This may increase the chance of side effects during treatment, especially sedation.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of xylometazoline in the elderly with use in other age groups.


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of xylometazoline. Make sure you tell your doctor if you have any other medical problems, especially:


  • Type 2 diabetes mellitus—Xylometazoline may worsen circulatory problems

  • Enlarged prostate—Urination difficulty may worsen due to constrictive effects of xylometazoline

  • Glaucoma—Xylometazoline may worsen the circulatory problems

  • Heart or blood vessel disease or

  • High blood pressure—Xylometazoline may make the condition worse

  • Overactive thyroid

Proper Use of xylometazoline


To use the nose drops:


  • Blow your nose gently. Tilt the head back while standing or sitting up. Place the drops into each nostril and immediately bend head forward toward the knees for a few seconds to allow the medicine to spread throughout the nose.

  • Rinse the dropper with hot water and dry with a clean tissue. Replace the cap right after use.

To use the nose spray:


  • Blow your nose gently. With the head upright, spray the medicine into each nostril. Sniff briskly while squeezing the bottle quickly and firmly. For best results, spray once into each nostril, wait 3 to 5 minutes to allow the medicine to work, then blow your nose gently and thoroughly. Repeat until the complete dose is used.

  • Rinse the tip of the spray bottle with hot water taking care not to suck water into the bottle, and dry with a clean tissue. Replace the cap right after use.

To avoid spreading the infection, do not use the container for more than one person.


Use xylometazoline only as directed. Do not use more of it, do not use it more often, and do not use it for longer than 3 days, unless otherwise directed by your doctor. To do so may make your runny or stuffy nose worse and may also increase the chance of side effects.


Dosing


The dose of xylometazoline will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of xylometazoline. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For stuffy nose:
    • For nasal solution (nose drops or nose spray) dosage forms:
      • Adults and children 12 years of age and older—Use one to three drops or sprays of a 0.1% solution in each nostril every eight to ten hours as needed.

      • Children 2 to 12 years of age—Use two or three drops or sprays of a 0.05% solution in each nostril every eight to ten hours as needed.

      • Children up to 2 years of age—Use and dose must be determined by your doctor.

      • The following dosage guidelines are used in Canada for children up to 12 years of age:
        • Children 6 to 12 years of age—Use two or three drops or sprays of a 0.05% solution in each nostril every eight to ten hours as needed.

        • Children up to 6 years of age—Use one drop or spray of a 0.05% solution in each nostril every eight to ten hours as needed.




Missed Dose


If you miss a dose of xylometazoline, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


xylometazoline Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


Symptoms of too much medicine being absorbed into the body
  • Blurred vision

  • dizziness

  • headache or light-headedness

  • hives

  • nausea

  • nervousness

  • pounding, irregular, or fast heartbeat

  • rash

  • shortness of breath

  • swelling of eyelids, face, or lips

  • troubled breathing

  • trouble in sleeping

  • wheezing

  • Increase in runny or stuffy nose

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  • Burning, dryness, or stinging of inside of nose

  • discharge of fluid from the nose

  • sneezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: xylometazoline Nasal side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More xylometazoline Nasal resources


  • Xylometazoline Nasal Side Effects (in more detail)
  • Xylometazoline Nasal Use in Pregnancy & Breastfeeding
  • Xylometazoline Nasal Drug Interactions
  • Xylometazoline Nasal Support Group
  • 4 Reviews for Xylometazoline Nasal - Add your own review/rating


  • xylometazoline nasal Concise Consumer Information (Cerner Multum)



Compare xylometazoline Nasal with other medications


  • Nasal Congestion

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Warfarina




Warfarina may be available in the countries listed below.


Ingredient matches for Warfarina



Warfarin

Warfarin is reported as an ingredient of Warfarina in the following countries:


  • Peru

International Drug Name Search

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Angiolingual




Angiolingual may be available in the countries listed below.


Ingredient matches for Angiolingual



Nitroglycerin

Nitroglycerin is reported as an ingredient of Angiolingual in the following countries:


  • Chile

International Drug Name Search

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Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate)


Pronunciation: AN-tye-HEE-moe-FIL-ik
Generic Name: Antihemophilic Factor (Recombinant) (Plasma/Albumin Free)
Brand Name: Advate


Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) is used for:

Preventing and controlling bleeding in patients with hemophilia A (factor VIII deficiency), including in surgical settings.


Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) is a manmade clotting factor. It works by increasing the amount of clotting factor VIII in the body, which helps the blood clot normally.


Do NOT use Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) if:


  • you are allergic to any ingredient in Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate), including mouse or hamster proteins

Contact your doctor or health care provider right away if any of these apply to you.



Before using Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate):


Some medical conditions may interact with Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have von Willebrand disease

  • if you have been told that you have inhibitors to factor VIII

Some MEDICINES MAY INTERACT with Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). However, no specific interactions with Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) are known at this time.


Ask your health care provider if Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate):


Use Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An additional patient leaflet is available with Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). Talk to your pharmacist if you have questions about this information.

  • Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) at home, carefully follow the injection procedures taught to you by your health care provider.

  • Your doctor or other health care provider will give you detailed instructions on how to mix and administer Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) if you will be using it at home. Instructions are also included in the patient leaflet that is available with Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). Be sure you understand how to give Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) before you administer a dose. If you have any questions or concerns, contact your doctor or other health care provider.

  • If Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.

  • When drawing a dose into a syringe, be sure to follow the procedure demonstrated to you by your doctor to prevent contamination of the vial, syringe, or medicine. Never touch the rubber stopper of the vial or the needle of the syringe with your fingers.

  • Carefully check that you have drawn the correct dose before administration.

  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.

  • If you miss a dose of Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate), contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate).



Important safety information:


  • Tell your doctor right away if bleeding is not controlled after using Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate).

  • Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) with caution. Do not drive or perform any other possibly unsafe tasks until you know how you react to it.

  • Patients receiving clotting factors sometimes develop antibodies or inhibitors to the medicine. This makes it less effective. If Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) stops working or does not work as well as it has before, contact your doctor immediately for instructions.

  • Tell your doctor or dentist that you take Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) before you receive any medical or dental care, emergency care, or surgery.

  • Talk with your doctor before you travel while you are using Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). Be sure to take along enough of Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) for your treatment while you are traveling

  • Lab tests, including factor VIII levels, may be performed while you take Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • PREGNANCY and BREAST-FEEDING: It is not known if Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) while you are pregnant. It is not known if Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) is found in breast milk. If you are or will be breast-feeding while you are using Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate), check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate):


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Cough; diarrhea; headache; joint pain; sore throat; stuffy or runny nose; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness); burning numbness, or tingling; chest pain; dizziness; fainting; fever or chills; hot flashes; light-headedness; nausea; pain, swelling, or redness at the injection site; severe headache; shortness of breath; swelling of the legs; unusual bruising.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate):

Store Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. You may also store Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) at room temperature, below 86 degrees F (30 degrees C), for up to 6 months. Once Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) has been kept at room temperature, do not return it to the refrigerator. Do not use Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) if the expiration date on the product has passed. Once Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) has been mixed, it must be used within 3 hours. Do not refrigerate after mixing. Discard any medicine remaining in the vial after you use it. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) out of the reach of children and away from pets.


General information:


  • If you have any questions about Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate), please talk with your doctor, pharmacist, or other health care provider.

  • Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate). If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) resources


  • Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) Side Effects (in more detail)
  • Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) Use in Pregnancy & Breastfeeding
  • Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) Support Group
  • 0 Reviews for Antihemophilic Factor (Recombinant) (Plasma/Albumin Free) (Advate) - Add your own review/rating


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Helvevir




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Aciclovir is reported as an ingredient of Helvevir in the following countries:


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Monday, September 26, 2016

Tamsulosine Biogaran




Tamsulosine Biogaran may be available in the countries listed below.


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Tamsulosin

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  • France

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Famotidin Alkaloid




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Famotidine

Famotidine is reported as an ingredient of Famotidin Alkaloid in the following countries:


  • Bulgaria

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Apo-Primidone




Apo-Primidone may be available in the countries listed below.


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Primidone

Primidone is reported as an ingredient of Apo-Primidone in the following countries:


  • Canada

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Clarazole




Clarazole may be available in the countries listed below.


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Ketoconazole is reported as an ingredient of Clarazole in the following countries:


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Gelcen




Gelcen may be available in the countries listed below.


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Capsaicin is reported as an ingredient of Gelcen in the following countries:


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Eperisone Hydrochloride




Eperisone Hydrochloride may be available in the countries listed below.


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Eperisone

Eperisone Hydrochloride (JAN) is also known as Eperisone (Rec.INN)

International Drug Name Search

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JANJapanese Accepted Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

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Apo-Rami




Apo-Rami may be available in the countries listed below.


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Ramipril

Ramipril is reported as an ingredient of Apo-Rami in the following countries:


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Friday, September 23, 2016

Amoxicilina + ácido clavulânico Generis




Amoxicilina + ácido clavulânico Generis may be available in the countries listed below.


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Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Amoxicilina + ácido clavulânico Generis in the following countries:


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Clavulanic Acid potassium (a derivative of Clavulanic Acid) is reported as an ingredient of Amoxicilina + ácido clavulânico Generis in the following countries:


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Loteprednol Etabonate




Loteprednol Etabonate may be available in the countries listed below.


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Loteprednol

Loteprednol Etabonate (BANM, USAN) is known as Loteprednol in the US.

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
USANUnited States Adopted Name

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Alfoxan




Alfoxan may be available in the countries listed below.


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Mefenamic Acid

Mefenamic Acid is reported as an ingredient of Alfoxan in the following countries:


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Amidotrizoic Acid




Amidotrizoic Acid may be available in the countries listed below.


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Sodium Amidotrizoate

Amidotrizoic Acid (BAN, JAN) is also known as Sodium Amidotrizoate (Rec.INN)

International Drug Name Search

Glossary

BANBritish Approved Name
JANJapanese Accepted Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

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Thursday, September 22, 2016

Vesicare



Generic Name: Solifenacin Succinate
Class: Genitourinary Smooth Muscle Relaxants
Chemical Name: (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate cmpd. with butanedioic acid (1:1)
Molecular Formula: C23H26N2O2•C4H6O4
CAS Number: 242478-38-2

Introduction

Genitourinary antispasmodic agent; an antimuscarinic agent.1


Uses for Vesicare


Overactive Bladder


Relief of symptoms associated with voiding (e.g., urge urinary incontinence, urgency, frequency).1


Vesicare Dosage and Administration


Administration


Oral Administration


Administer orally once daily with liquids without regard to meals.1 8


Swallow tablets whole.1 8


Dosage


Available as solifenacin succinate; dosage expressed in terms of the salt.1


Adults


Overactive Bladder

Oral

Initially, 5 mg once daily.1 If well tolerated, may increase to 10 mg once daily.1


Prescribing Limits


Adults


Overactive Bladder

Oral

Maximum 10 mg daily.1


Special Populations


Hepatic Impairment


Maximum 5 mg daily in patients with moderate hepatic impairment (Child-Pugh class B).1 (See Elimination: Special Populations, under Pharmacokinetics.)


Use not recommended in patients with severe hepatic impairment (Child-Pugh class C).1


Renal Impairment


Maximum 5 mg daily in patients with severe renal impairment (Clcr <30 mL/minute).1 (See Elimination: Special Populations, under Pharmacokinetics.)


Cautions for Vesicare


Contraindications



  • Urinary retention, gastric retention, or uncontrolled angle-closure glaucoma.1




  • Known hypersensitivity to solifenacin succinate or any ingredient in the formulation.1



Warnings/Precautions


Sensitivity Reactions


Angioedema

Angioedema reported in at least 1 patient.1 9


General Precautions


Urinary Retention

Risk of urinary retention; use with caution in patients with clinically important bladder outflow obstruction.1


Decreased GI Motility

Use with caution in patients with decreased GI motility1 (e.g., patients with severe constipation, ulcerative colitis, or myasthenia gravis) or obstructive GI disorders.9


Fecal impaction, colonic obstruction, and intestinal obstruction reported rarely with 10-mg daily dosage.1


Prolongation of QT Interval

30-mg daily dosage associated with more pronounced prolongation of QT interval than 10-mg daily dosage.1 (See Prescribing Limits under Dosage and Administration.) Consider this observation when deciding to use solifenacin in patients with history of QT interval prolongation or receiving drugs that prolong QT interval.1


Controlled Angle-closure Glaucoma

Use with caution in patients being treated for angle-closure glaucoma.1 (See Contraindications under Cautions.)


Specific Populations


Pregnancy

Category C.1


Lactation

Distributed into milk in mice; not known whether distributed into human milk.1 Discontinue nursing or the drug.1


Pediatric Use

Safety and efficacy not established in children <18 years of age.9


Geriatric Use

No substantial differences in safety and efficacy relative to younger adults.1 (See Elimination: Special Populations, under Pharmacokinetics.)


Hepatic Impairment

Use with caution.1 (See Hepatic Impairment under Dosage and Administration and see Elimination: Special Populations, under Pharmacokinetics.)


Use not recommended in patients with severe hepatic impairment (Child-Pugh class C).1


Renal Impairment

Use with caution.1 (See Renal Impairment under Dosage and Administration and see Elimination: Special Populations, under Pharmacokinetics.)


Common Adverse Effects


Dry mouth, constipation.1


Interactions for Vesicare


Metabolized principally by CYP3A4.1 Does not inhibit CYP1A1/2, 2C9, 2C19, 2D6, or 3A4.1


Drugs Affecting Hepatic Microsomal Enzymes


Inhibitors of CYP3A4: Potential pharmacokinetic interaction (increased plasma solifenacin concentrations).1 Do not exceed 5 mg daily when used concomitantly with potent inhibitors of CYP3A4.1 (See Specific Drugs under Interactions.)


Inducers of CYP3A4: Potential pharmacokinetic interaction (altered solifenacin pharmacokinetics).1


Drugs Metabolized by Hepatic Microsomal Enzymes


Substrates of CYP1A1/2, CYP2C9, CYP2C19, CYP2D6, or CYP3A4: Pharmacokinetic interaction unlikely


Drugs Affected by GI Motility


Potential pharmacokinetic interaction (altered absorption because of decreased GI motility).10 (See Decreased GI Motility under Cautions.)


Specific Drugs





















Drug



Interaction



Comments



Anticholinergic agents



Possible additive anticholinergic effects9



Digoxin



No substantial effect on digoxin pharmacokinetics1



Hormonal contraceptives



No substantial changes in plasma concentrations of ethinyl estradiol or levonorgestrel1



Ketoconazole



Increased plasma solifenacin concentrations1



Do not exceed a solifenacin succinate dosage of 5 mg daily1



Warfarin



No substantial effect on warfarin pharmacokinetics1


Vesicare Pharmacokinetics


Absorption


Bioavailability


Absolute bioavailability is approximately 90%.1 6


Peak plasma concentrations achieved within 3–8 hours after administration.1


Food


Food does not affect pharmacokinetics of solifenacin.1 7


Special Populations


Increased plasma concentrations reported in geriatric patients, patients with moderate hepatic impairment (Child-Pugh class B), and patients with severe renal impairment (Clcr <30 mL/minute).1 (See Special Populations under Dosage and Administration and see Elimination: Special Populations, under Pharmacokinetics.)


Distribution


Extent


Highly distributed to tissues outside the CNS.1


Distributed into milk in mice; not known whether distributed into human milk.1


Plasma Protein Binding


Approximately 98% (mainly to α1-acid glycoprotein).1


Elimination


Metabolism


Extensively metabolized in the liver, mainly via CYP3A4.1


Elimination Route


Excreted in urine (approximately 69%) and in feces (approximately 23%); unchanged drug accounts for <15% of recovered radioactivity.1


Half-life


45–68 hours following long-term administration.1


Special Populations


Prolonged half-life in geriatric patients, patients with moderate hepatic impairment (Child-Pugh class B), and patients with severe renal impairment (Clcr <30 mL/minute).1 (See Special Populations under Dosage and Administration.)


Stability


Storage


Oral


Tablets

25°C (may be exposed to 15–30°C).1


ActionsActions



  • Potent and selective antimuscarinic agent.1 2




  • Inhibits contraction of the detrusor muscle of the bladder, resulting in decreased bladder activity.2




  • Demonstrates binding specificity for muscarinic M3 receptors in vitro and functional selectivity for urinary bladder over secretory (e.g., salivary) glands.2



Advice to Patients



  • Risk of blurred vision, constipation, dry mouth, and heat prostration (when used in a hot environment).1 Use caution when driving or performing dangerous activities until effects on vision are known.8 Consult a clinician if severe abdominal pain occurs or if constipation persists for ≥3 days.1




  • Importance of taking solifenacin succinate with liquids and swallowing the tablet whole.1 8 If a dose is skipped, resume therapy the next day; do not take 2 doses in the same day.8




  • Importance of reading manufacturer’s patient information leaflet before initiating therapy.1




  • Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs and dietary or herbal supplements, as well as any concomitant illnesses.1




  • Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed.1




  • Importance of informing patients of other important precautionary information. (See Cautions.)



Preparations


Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.


















Solifenacin Succinate

Routes



Dosage Forms



Strengths



Brand Names



Manufacturer



Oral



Tablets, film-coated



5 mg



Vesicare



Yamanouchi (also promoted by GlaxoSmithKline)



10 mg



Vesicare



Yamanouchi (also promoted by GlaxoSmithKline)


Comparative Pricing


This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 03/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.


VESIcare 10MG Tablets (ASTELLAS): 30/$161.99 or 90/$458.96


VESIcare 5MG Tablets (ASTELLAS): 30/$165.98 or 90/$475.95



Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.


The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions July 2005. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.




References



1. Yamanouchi. VESIcare (solifenacin succinate) tablets prescribing information. Paramus, NJ; 2004 Nov.



2. Chilman-Blair K. Solifenacin: Treatment of overactive bladder. Drugs Today. 2004; 40:343-53. [PubMed 15190387]



3. Chapple CR, Rechberger T, Al-Shukri S et al. Randomized, double-blind placebo- and tolterodine-controlled trial of the once-daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladder. BJU Int. 2004; 93:303-10. [IDIS 532014] [PubMed 14764127]



4. Cardozo L, Lisec M, Millard R et al. Randomized, double-blind placebo controlled trial of the once daily antimuscarinic agent solifenacin succinate in patients with overactive bladder. J Urol. 2004; 172:1919-24. [IDIS 522716] [PubMed 15540755]



5. Kelleher CJ, Cardozo L, Chapple CR et al. Improved quality of life in patients with overactive bladder symptoms treated with solifenacin. BJU Int. 2005; 95:81-5. [IDIS 532015] [PubMed 15638900]



6. Kuipers ME, Krauwinkel WJJ, Mulder H et al. Solifenacin demonstrates high absolute bioavailability in healthy men. Drugs R D. 2004; 5:73-81. [PubMed 15293866]



7. Uchida T, Krauwinkel WJ, Mulder H et al. Food does not affect the pharmacokinetics of solifenacin, a new muscarinic receptor antagonist: results of a randomized crossover trial. Br J Clin Pharmacol. 2004; 58:4-7. [IDIS 519282] [PubMed 15206986]



8. Yamanouchi. VESIcare (solifenacin succinate) patient information. Paramus, NJ; 2004 Nov.



9. Astellas Pharma, Durham, NC: Personal communication.



10. Novartis. Enablex (darifenacin hydrobromide) extended-release tablets prescribing information. East Hanover, NJ; 2004 Dec.



More Vesicare resources


  • Vesicare Side Effects (in more detail)
  • Vesicare Use in Pregnancy & Breastfeeding
  • Drug Images
  • Vesicare Drug Interactions
  • Vesicare Support Group
  • 31 Reviews for Vesicare - Add your own review/rating


  • Vesicare Advanced Consumer (Micromedex) - Includes Dosage Information

  • Vesicare Consumer Overview

  • VESIcare Prescribing Information (FDA)

  • VESIcare MedFacts Consumer Leaflet (Wolters Kluwer)



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Azur compositum




Azur compositum may be available in the countries listed below.


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Codeine phosphate hemihydrate (a derivative of Codeine) is reported as an ingredient of Azur compositum in the following countries:


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Meiclox may be available in the countries listed below.


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Cloxacillin sodium salt (a derivative of Cloxacillin) is reported as an ingredient of Meiclox in the following countries:


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Wednesday, September 21, 2016

Sodium Nitrite




In the US, Sodium Nitrite is a member of the drug class antidotes.

Scheme

USAN

ATC (Anatomical Therapeutic Chemical Classification)

V03AB08

CAS registry number (Chemical Abstracts Service)

0007632-00-0

Chemical Formula

Na-N-O2

Molecular Weight

69

Therapeutic Categories

Antidote

Vasodilator

Chemical Name

Nitrous acid, sodium salt (USAN)

Foreign Names

  • Natrii nitris (Latin)
  • Natrium nitrit (German)
  • Nitrite de sodium (French)

Generic Names

  • Natriumnitrit (OS: IUPAC)
  • CCRIS 559 (IS)
  • Erinitrit (IS)
  • Filmerine (IS)
  • HSDB 757 (IS)
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  • Synfat 1004 (IS)
  • Natrii nitris (PH: Ph. Int. 4, Ph. Eur. 6)
  • Natriumnitrit (PH: Ph. Eur. 6)
  • Sodium Nitrite (PH: BP 2010, Ph. Int. 4, USP 32, Ph. Eur. 6)

Brand Names

  • Sodium Nitrite
    Hospira, Australia; Hospira, New Zealand; Phebra, Australia

International Drug Name Search

Glossary

IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
USANUnited States Adopted Name

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Alstat




Alstat may be available in the countries listed below.


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Etamsylate

Etamsylate is reported as an ingredient of Alstat in the following countries:


  • India

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Simvagen




Simvagen may be available in the countries listed below.


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Simvastatin

Simvastatin is reported as an ingredient of Simvagen in the following countries:


  • Oman

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Vinblastina Mayne




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Vinblastine

Vinblastine sulfate (a derivative of Vinblastine) is reported as an ingredient of Vinblastina Mayne in the following countries:


  • Spain

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Aironyl




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Terbutaline

Terbutaline sulfate (a derivative of Terbutaline) is reported as an ingredient of Aironyl in the following countries:


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Aquasol E




In the US, Aquasol E (vitamin e systemic) is a member of the drug class vitamins and is used to treat Alzheimer's Disease, Anemia - Sickle Cell, Cystic Fibrosis, Dietary Supplementation, Nocturnal Leg Cramps, Retinopathy Prophylaxis, Tardive Dyskinesia and Vitamin E Deficiency.

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  • Aquasol E

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Tocopherol, α-

Tocopherol, α- acetate (a derivative of Tocopherol, α-) is reported as an ingredient of Aquasol E in the following countries:


  • Colombia

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Tuesday, September 20, 2016

Aceptin-R




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Ranitidine

Ranitidine is reported as an ingredient of Aceptin-R in the following countries:


  • Bangladesh

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Amoxi-Tablinen




Amoxi-Tablinen may be available in the countries listed below.


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Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Amoxi-Tablinen in the following countries:


  • Germany

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Adoair




Adoair may be available in the countries listed below.


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Fluticasone

Fluticasone propionate (a derivative of Fluticasone) is reported as an ingredient of Adoair in the following countries:


  • Japan

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Salmeterol xinafoate (a derivative of Salmeterol) is reported as an ingredient of Adoair in the following countries:


  • Japan

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Amphojel




In the US, Amphojel (aluminum hydroxide systemic) is a member of the drug class antacids and is used to treat Duodenal Ulcer, Erosive Esophagitis, Gastrointestinal Hemorrhage, GERD, Hyperphosphatemia, Indigestion, Peptic Ulcer, Stomach Ulcer and Zollinger-Ellison Syndrome.

US matches:

  • Amphojel

Ingredient matches for Amphojel



Aluminium Hydroxide

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acetaminophen, sodium bicarbonate, and citric acid



a-seet-a-MIN-oh-fen, SOE-dee-um bye-KAR-bo-nate, SIT-rik AS-id


Available Dosage Forms:


  • Granule

Therapeutic Class: Acetaminophen Combination


Uses For acetaminophen, sodium bicarbonate, and citric acid

Acetaminophen, sodium bicarbonate, and citric acid combination is used to relieve pain occurring together with heartburn, sour stomach, or acid indigestion. The acetaminophen in this combination medicine is the pain reliever. The sodium bicarbonate in acetaminophen, sodium bicarbonate, and citric acid is an antacid. It neutralizes stomach acid by combining with it to form a new substance that is not an acid.


acetaminophen, sodium bicarbonate, and citric acid is available without a prescription.


Before Using acetaminophen, sodium bicarbonate, and citric acid


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For acetaminophen, sodium bicarbonate, and citric acid, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to acetaminophen, sodium bicarbonate, and citric acid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Acetaminophen has been tested in children and has not been shown to cause different side effects or problems than it does in adults. However, sodium bicarbonate should not be given to young children (under 6 years of age) unless ordered by their doctor. Small children with stomach problems usually cannot describe their symptoms very well. They should be checked by a doctor, because they may have a condition that needs other treatment.


Geriatric


Acetaminophen has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults. However, the large amount of sodium in this combination medicine can be harmful to some elderly people. Therefore, it is best that older people not use acetaminophen, sodium bicarbonate, and citric acid for more than 5 days in a row, unless otherwise directed by their doctor.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Citric AcidPotassium Citrate

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Sodium BicarbonateAcetaminophen

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking acetaminophen, sodium bicarbonate, and citric acid, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using acetaminophen, sodium bicarbonate, and citric acid with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acenocoumarol

  • Carbamazepine

  • Dasatinib

  • Isoniazid

  • Itraconazole

  • Phenytoin

  • Warfarin

  • Zidovudine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using acetaminophen, sodium bicarbonate, and citric acid with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use acetaminophen, sodium bicarbonate, and citric acid, or give you special instructions about the use of food, alcohol, or tobacco.


  • Ethanol

Using acetaminophen, sodium bicarbonate, and citric acid with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use acetaminophen, sodium bicarbonate, and citric acid, or give you special instructions about the use of food, alcohol, or tobacco.


  • Cabbage

Other Medical Problems


The presence of other medical problems may affect the use of acetaminophen, sodium bicarbonate, and citric acid. Make sure you tell your doctor if you have any other medical problems, especially:


  • Alcohol abuse or

  • Hepatitis or other liver disease—The chance of serious side effects, including liver damage, may be increased

  • Appendicitis (symptoms of, such as stomach or lower abdominal pain, cramping, bloating, soreness, nausea, or vomiting)—Sodium bicarbonate can make your condition worse; also, people who may have appendicitis need medical attention and should not try to treat themselves

  • Edema (swelling of face, fingers, feet, or lower legs caused by too much water in the body) or

  • Heart disease or

  • High blood pressure or

  • Toxemia of pregnancy—The sodium in this combination medicine can make these conditions worse

  • Kidney disease—The chance of serious side effects may be increased

Proper Use of acetaminophen, sodium bicarbonate, and citric acid


Make certain your health care professional knows if you are on a low-sodium, low-sugar, or any other special diet. acetaminophen, sodium bicarbonate, and citric acid contains a large amount of sodium (more than 750 mg for each 325 mg of acetaminophen).


Unless otherwise directed by your doctor, do not take more of acetaminophen, sodium bicarbonate, and citric acid than is recommended on the package label. If too much is taken, liver damage or other serious side effects may occur.


To use acetaminophen, sodium bicarbonate, and citric acid:


  • acetaminophen, sodium bicarbonate, and citric acid must be taken in the form of a liquid that is made from the effervescent granules. Do not swallow the granules themselves.

  • To make the liquid, pour the amount of effervescent granules directed on the package into a glass. Then add ½ glass (4 ounces) of cool water.

  • Drink all of the liquid. You may drink the liquid while it is still fizzing or after the fizzing stops.

  • Add a little more water to the glass and drink that, to make sure that you get the full amount of the medicine.

Dosing


The dose of acetaminophen, sodium bicarbonate, and citric acid will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of acetaminophen, sodium bicarbonate, and citric acid. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (effervescent granules):
    • For pain and upset stomach:
      • Adults and teenagers—325 to 650 milligrams (mg) of acetaminophen, dissolved in water, every four hours as needed. The bottle cap can be used to measure the dose. There are 325 mg of acetaminophen in three-fourths of a capful.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of acetaminophen, sodium bicarbonate, and citric acid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using acetaminophen, sodium bicarbonate, and citric acid


If you will be taking acetaminophen, sodium bicarbonate, and citric acid for a long time (more than 10 days in a row), your doctor should check your progress at regular visits.


Check with your doctor if your pain and/or upset stomach last for more than 10 days or if they get worse, if new symptoms occur, or if the painful area is red or swollen. These could be signs of a serious condition that needs medical treatment.


The sodium bicarbonate in this combination medicine can keep other medicines from working properly if the 2 medicines are taken too close together. Always take acetaminophen, sodium bicarbonate, and citric acid:


  • At least 6 hours before or 2 hours after taking ciprofloxacin (e.g., Cipro) or lomefloxacin (e.g., Maxaquin).

  • At least 8 hours before or 2 hours after taking enoxacin (e.g., Penetrex).

  • At least 2 hours after taking itraconazole (e.g., Sporanox).

  • At least 3 hours before or after taking ketoconazole (e.g., Nizoral).

  • At least 2 hours before or after taking norfloxacin (e.g., Noroxin) or ofloxacin (e.g., Floxin).

  • At least 3 or 4 hours before or after taking a tetracycline antibiotic by mouth.

  • At least 1 or 2 hours before or after taking any other medicine by mouth.

Check the labels of all nonprescription (over-the-counter [OTC]) and prescription medicines you now take. If any contain acetaminophen or sodium, check with your health care professional . Taking them together with acetaminophen, sodium bicarbonate, and citric acid may cause an overdose.


Taking certain other medicines together with acetaminophen may increase the chance of unwanted effects. The risk will depend on how much of each medicine you take every day, and on how long you take the medicines together. If your medical doctor or dentist directs you to take these medicines together on a regular basis, follow his or her directions carefully. However, do not take any of the following medicines together with acetaminophen for more than a few days, unless your doctor has directed you to do so and is following your progress:


  • Aspirin or other salicylates

  • Diclofenac (e.g., Voltaren)

  • Diflunisal (e.g., Dolobid)

  • Etodolac (e.g., Lodine)

  • Fenoprofen (e.g., Nalfon)

  • Floctafenine (e.g., Idarac)

  • Flurbiprofen, oral (e.g., Ansaid)

  • Ibuprofen (e.g., Motrin)

  • Indomethacin (e.g., Indocin)

  • Ketoprofen (e.g., Orudis)

  • Ketorolac (e.g., Toradol)

  • Meclofenamate (e.g., Meclomen)

  • Mefenamic acid (e.g., Ponstel)

  • Nabumetone (e.g., Relafen)

  • Naproxen (e.g., Naprosyn)

  • Oxaprozin (e.g., Daypro)

  • Phenylbutazone (e.g., Butazolidin)

  • Piroxicam (e.g., Feldene)

  • Sulindac (e.g., Clinoril)

  • Tenoxicam (e.g., Mobiflex)

  • Tiaprofenic acid (e.g., Surgam)

  • Tolmetin (e.g., Tolectin)

If you will be taking more than an occasional 1 or 2 doses of acetaminophen, sodium bicarbonate, and citric acid:


  • Do not drink alcoholic beverages. Drinking alcoholic beverages while you are taking acetaminophen may increase the chance of liver damage, especially if you drink large amounts of alcoholic beverages regularly, if you take more acetaminophen than is recommended on the package label, or if you take it regularly for a long time.

  • Do not also drink a lot of milk or eat a lot of milk products. To do so may increase the chance of side effects.

  • To prevent side effects caused by too much sodium in the body, you may need to limit the amount of sodium in the foods you eat. Some foods that contain large amounts of sodium are canned soup, canned vegetables, pickles, ketchup, green and ripe (black) olives, relish, frankfurters and other sausage-type meats, soy sauce, and carbonated beverages. If you have any questions about this, check with your health care professional.

Acetaminophen may interfere with the results of some medical tests. Before you have any medical tests, tell the person in charge if you have taken acetaminophen within the past 3 or 4 days. If possible, it is best to call the laboratory where the test will be done about 4 days ahead of time, to find out whether acetaminophen, sodium bicarbonate, and citric acid may be taken during the 3 or 4 days before the test.


For diabetic patients:


  • Acetaminophen may cause false results with some blood glucose (sugar) tests. If you notice any change in your test results, or if you have any questions about this possible problem, check with your health care professional. This is especially important if your diabetes is not well-controlled.

If you think that you or anyone else may have taken an overdose of acetaminophen, sodium bicarbonate, and citric acid, get emergency help at once, even if there are no signs of poisoning. Signs of severe acetaminophen poisoning may not appear for 2 to 4 days after the overdose is taken, but treatment to prevent liver damage or death must be started as soon as possible. Treatment started more than 24 hours after the overdose is taken may not be effective.


acetaminophen, sodium bicarbonate, and citric acid Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although the following side effects occur very rarely when 1 or 2 doses of this combination medicine is taken occasionally, they may be more likely to occur if: too much medicine is taken, the medicine is taken several times a day, or the medicine is taken for more than a few days in a row.


Check with your doctor immediately if any of the following side effects occur:


Rare
  • Yellow eyes or skin

Symptoms of overdose
  • Diarrhea

  • increased sweating

  • loss of appetite

  • nausea or vomiting

  • stomach cramps or pain

  • swelling, pain, or tenderness in the upper abdomen or stomach area

Check with your doctor as soon as possible if any of the following side effects occur:


Less common or rare
  • Bloody or black, tarry stools

  • bloody or cloudy urine, frequent urge to urinate, or sudden decrease in amount of urine

  • fever with or without chills (not present before treatment and not caused by the condition being treated)

  • headache (continuing)

  • increased blood pressure

  • mood or mental changes

  • muscle pain or twitching

  • nervousness or restlessness

  • pain (severe and/or sharp) in lower back and/or side

  • skin rash, hives, or itching

  • slow breathing

  • sores, ulcers, or white spots on lips or in mouth

  • sore throat (not present before treatment and not caused by the condition being treated)

  • swelling of face, fingers, ankles, feet, or lower legs

  • unpleasant taste

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Increased thirst

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: acetaminophen, sodium bicarbonate, and citric acid side effects (in more detail)



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